RNAi Substractes - shRNA, siRNA and miRNA

RNA interference (RNAi) is a gene-silencing process in which RNA molecules inhibit gene expression by targeting mRNA. The key RNAi molecules regulating this process are small interfering RNAs (siRNA), microRNAs (miRNA) and short hairpin RNAs (shRNA).

RNAi molecules of 19 to 23 nucleotides are especially effective. And the efficiency of gene suppression is primarily dependent on the portion of the gene sequence targeted. Our services include:

   1) Identification of RNAi target sequence.
   2) Synthesis of the RNAi insert.
   3) Cloning the insert into the viral or non-viral delivery vector systems.
   4) Confirmation of the RNAi construct by sequencing.

Customers will receive:

   1) Desired RNAi construct DNA.
   2) Stab culture of E. coli carrying the RNAi construct.
   3) Sequencing chromatogram data.

Turnaround Time:

   Approximately 1~2 weeks.

Please contact us for a detailed quote or for more information.